|
KMID : 0371619870030010001
|
|
Journal of Wonkwang Medical Science
1987 Volume.3 No. 1 p.1 ~ p.8
|
|
|
A Study on the cytotoxic effect of trivalent and hexavalent chromium on cultured mouse fibroblast cells
|
|
鄭?塤/Chung, Chong Hoo
金在玟/崔玟圭/鄭然泰/Kim, Jae Min/Choi, Min Kyu/Chung, Yeun Tai
|
|
|
Abstract
|
|
|
This study was performed to investigate the cytotoxicity of the chromium ion on the mouse fibroblast L cell line. The effects of chromium ion (Cr". CO+) on the cell proliferation and the total amount of protein in cultured cells were investigated at various concentrations of chromium ion. The results were as follows ;
1. Cell proliferation and the total amount of protein were not influenced at I ppm, 5 ppm and 10ppm in Cr"? treated medium.
2. In 0.05 ppm containing medium, cell proliferation and the total amount
of protein were not changed comparing with control group, but in 0.lppm containing medium, they were slightly inhibited and completely inhibited at 0.5ppm in CO+ - treated medium.
From these results, it is suggested that the cell proliferation and protein synthesis were inhibited markedly by CO+ rather than by Cr´+.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|